A maximum likelihood QTL analysis reveals common genome regions controlling resistance to Salmonella colonization and carrier-state.

ABSTRACT:

Background

The serovars Enteritidis and Typhimurium of the Gram-negative bacterium Salmonella enterica are significant causes of human food poisoning. Fowl carrying these bacteria often show no clinical disease, with detection only established post-mortem. Increased resistance to the carrier state in commercial poultry could be a way to improve food safety by reducing the spread of these bacteria in poultry flocks. Previous studies identified QTLs for both resistance to carrier state and resistance to Salmonella colonization in the same White Leghorn inbred lines. Until now, none of the QTLs identified was common to the two types of resistance. All these analyses were performed using the F2 inbred or backcross option of the QTLExpress software based on linear regression. In the pre

SUBMITTER: Thanh-Son T 

PROVIDER: S-EPMC3428659 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature