Genomic characterization of the European sea bass Dicentrarchus labrax reveals the presence of a novel uncoupling protein (UCP) gene family member in the teleost fish lineage.

ABSTRACT:

Background

Uncoupling proteins (UCP) are evolutionary conserved mitochondrial carriers that control energy metabolism and therefore play important roles in several physiological processes such as thermogenesis, regulation of reactive oxygen species (ROS), growth control, lipid metabolism and regulation of insulin secretion. Despite their importance in various physiological processes, their molecular function remains controversial. The evolution and phylogenetic distribution may assist to identify their general biological function and structure-function relationships. The exact number of uncoupling protein genes in the fish genome and their evolution is unresolved.

Results

Here we report the first characterisation of UCP gene family members in sea bass, Dicentrarchus labrax,

SUBMITTER: Tine M 

PROVIDER: S-EPMC3428666 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature