Identification of a new prostate cancer susceptibility locus on chromosome 8q24.

ABSTRACT: We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We identify a new association with prostate cancer risk on chromosome 8q24 (rs620861, P = 1.3 x 10(-10), heterozygote OR = 1.17, 95% CI 1.10-1.24; homozygote OR = 1.33, 95% CI 1.21-1.45). This defines a new locus associated with prostate cancer susceptibility on 8q24.

SUBMITTER: Yeager M 

PROVIDER: S-EPMC3430510 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature