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Progress towards the synthesis of Urukthapelstatin A and two analogues.


ABSTRACT: We report our progress towards the synthesis of Urukthapelstatin A (Ustat A) and two analogues. Our retrosynthetic strategy involved the synthesis of three fragments: a tri-heteroaromatic moiety, a phenyl oxazole fragment, and a dipeptide. Described are the syntheses of three unique tri-heteroaromatic moieties. In addition, the corresponding linear precursors of Ustat A and two analogues are presented.

SUBMITTER: Pan CM 

PROVIDER: S-EPMC3431499 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature