Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study.

ABSTRACT:

Context

Endometrial cancer is associated with metabolic disturbances related to its underlying risk factors, including obesity and diabetes. Identifying metabolite biomarkers associated with endometrial cancer may have value for early detection, risk assessment, and understanding etiology.

Objective

The objective of the study was to evaluate the reliable measurement of metabolites in epidemiological studies with nonstandardized blood collection; confirm previously reported correlations of metabolites with body size; and assess differences in metabolite levels between cases and controls.

Design

This was the Polish Endometrial Cancer Study (2001-2003).

Setting

This study was a population-based case-control study.

Patients

Patients included 250 cases and 25

SUBMITTER: Gaudet MM 

PROVIDER: S-EPMC3431573 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature