Body fat abnormality in HIV-infected children and adolescents living in Europe: prevalence and risk factors.

ABSTRACT:

Objectives

To estimate the prevalence of and identify risk factors for lipodystrophy syndrome (LS) and body fat abnormality in a population of HIV-infected children and adolescents.

Design

Cross-sectional observational study.

Methods

HIV-infected subjects aged 2-18 years were recruited from 15 HIV centers in Belgium, Italy, and Poland between January 2007 and December 2008. Standardized assessments by the patient's long-term clinician were performed to establish the presence of abnormality. Risk factors were explored in logistic regression models for fat abnormality outcomes and LS (abnormality plus dyslipidemia).

Results

Among 426 subjects (70% white), median age was 12.2 years (interquartile range: 9.0-15.0 years) and median duration of antiretroviral therapy

SUBMITTER: Alam N 

PROVIDER: S-EPMC3433033 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature