An image analysis toolbox for high-throughput C. elegans assays.

ABSTRACT: We present a toolbox for high-throughput screening of image-based Caenorhabditis elegans phenotypes. The image analysis algorithms measure morphological phenotypes in individual worms and are effective for a variety of assays and imaging systems. This WormToolbox is available through the open-source CellProfiler project and enables objective scoring of whole-worm high-throughput image-based assays of C. elegans for the study of diverse biological pathways that are relevant to human disease.

SUBMITTER: Wahlby C 

PROVIDER: S-EPMC3433711 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature