Influence of perioperative oxygen fraction on pulmonary function after abdominal surgery: a randomized controlled trial.

ABSTRACT:

Background

A high perioperative inspiratory oxygen fraction (FiO2) may reduce the frequency of surgical site infection. Perioperative atelectasis is caused by absorption, compression and reduced function of surfactant. It is well accepted, that ventilation with 100% oxygen for only a few minutes is associated with significant formation of atelectasis. However, it is still not clear if a longer period of 80% oxygen results in more atelectasis compared to a low FiO2.Our aim was to assess if a high FiO2 is associated with impaired oxygenation and decreased pulmonary functional residual capacity (FRC).

Methods

Thirty-five patients scheduled for laparotomy for ovarian cancer were randomized to receive either 30% oxygen (n = 15) or 80% oxygen (n = 20) during and for 2 h after surg

SUBMITTER: Staehr AK 

PROVIDER: S-EPMC3434073 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature