CONS-COCOMAPS: a novel tool to measure and visualize the conservation of inter-residue contacts in multiple docking solutions.

ABSTRACT:

Background

The development of accurate protein-protein docking programs is making this kind of simulations an effective tool to predict the 3D structure and the surface of interaction between the molecular partners in macromolecular complexes. However, correctly scoring multiple docking solutions is still an open problem. As a consequence, the accurate and tedious screening of many docking models is usually required in the analysis step.

Methods

All the programs under CONS-COCOMAPS have been written in python, taking advantage of python libraries such as SciPy and Matplotlib. CONS-COCOMAPS is freely available as a web tool at the URL:http://www.molnac.unisa.it/BioTools/conscocomaps/.

Results

Here we presented CONS-COCOMAPS, a novel tool to easily measure and visualize

SUBMITTER: Vangone A 

PROVIDER: S-EPMC3434444 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature