Hierarchical organization of gamma and theta oscillatory dynamics in schizophrenia.

ABSTRACT:

Background

Schizophrenia patients have deficits across a broad range of important cognitive and clinical domains. Synchronization of oscillations in the gamma frequency range (~40 Hz) is associated with many normal cognitive functions and underlies at least some of the deficits observed in schizophrenia patients. Recent studies have demonstrated that gamma oscillations are modulated by the phase of theta waves, and this cross-frequency coupling indicates that a complex and hierarchical organization governs neural oscillatory dynamics. The aims of the present study were to determine if schizophrenia patients have abnormalities in the amplitude, synchrony, and cross-frequency coupling of gamma and theta oscillations in response to gamma-frequency steady-state stimulation and if abnor

SUBMITTER: Kirihara K 

PROVIDER: S-EPMC3434875 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature