Ancient origin of the divergent forms of leucyl-tRNA synthetases in the Halobacteriales.

ABSTRACT:

Background

Horizontal gene transfer (HGT) has greatly impacted the genealogical history of many lineages, particularly for prokaryotes, with genes frequently moving in and out of a line of descent. Many genes that were acquired by a lineage in the past likely originated from ancestral relatives that have since gone extinct. During the course of evolution, HGT has played an essential role in the origin and dissemination of genetic and metabolic novelty.

Results

Three divergent forms of leucyl-tRNA synthetase (LeuRS) exist in the archaeal order Halobacteriales, commonly known as haloarchaea. Few haloarchaeal genomes have the typical archaeal form of this enzyme and phylogenetic analysis indicates it clusters within the Euryarchaeota as expected. The majority of sequenced halob

SUBMITTER: Andam CP 

PROVIDER: S-EPMC3436685 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature