The involvement of thaumatin-like proteins in plant food cross-reactivity: a multicenter study using a specific protein microarray.

ABSTRACT: Cross-reactivity of plant foods is an important phenomenon in allergy, with geographical variations with respect to the number and prevalence of the allergens involved in this process, whose complexity requires detailed studies. We have addressed the role of thaumatin-like proteins (TLPs) in cross-reactivity between fruit and pollen allergies. A representative panel of 16 purified TLPs was printed onto an allergen microarray. The proteins selected belonged to the sources most frequently associated with peach allergy in representative regions of Spain. Sera from two groups of well characterized patients, one with allergy to Rosaceae fruit (FAG) and another against pollens but tolerant to food-plant allergens (PAG), were obtained from seven geographical areas with different environmental pol

SUBMITTER: Palacin A 

PROVIDER: S-EPMC3436791 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature