Phylogenetic analysis of torque teno virus in hepatitis C virus infected patients in shiraz.

ABSTRACT:

Background

Torque teno virus (TTV) was the first human Circoviridae detected in a Japanese patient with unknown hepatitis in 1997. Subsequently, several studies performed to evaluate different aspects of Torque teno virus pathogenesis.

Objectives

The present study aimed to determine dominant genotype of Torque teno virus in chronic hepatitis disease using 5΄-UTR sequence among patients infected by hepatitis C virus in Shiraz - Iran.

Patients and methods

The study conducted in 240 patients with chronic hepatitis C from Prof. Alborzi Clinical Microbiology Research Center. The presence of Torque teno virus DNA and its genotype in plasma was assessed by nested polymerase chain reaction using two primer sets for 5΄-UTR and N22 regions. Phylogenetic analysis was performed b

SUBMITTER: Kenar Koohi A 

PROVIDER: S-EPMC3437454 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature