NetWalker: a contextual network analysis tool for functional genomics.

ABSTRACT:

Background

Functional analyses of genomic data within the context of a priori biomolecular networks can give valuable mechanistic insights. However, such analyses are not a trivial task, owing to the complexity of biological networks and lack of computational methods for their effective integration with experimental data.

Results

We developed a software application suite, NetWalker, as a one-stop platform featuring a number of novel holistic (i.e. assesses the whole data distribution without requiring data cutoffs) data integration and analysis methods for network-based comparative interpretations of genome-scale data. The central analysis components, NetWalk and FunWalk, are novel random walk-based network analysis methods that provide unique analysis capabilities to assess

SUBMITTER: Komurov K 

PROVIDER: S-EPMC3439272 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature