Aerosolized avian influenza virus by laboratory manipulations.

ABSTRACT:

Background

Avian H5N1 influenza viruses present a challenge in the laboratory environment, as they are difficult to collect from the air due to their small size and relatively low concentration. In an effort to generate effective methods of H5N1 air removal and ensure the safety of laboratory personnel, this study was designed to investigate the characteristics of aerosolized H5N1 produced by laboratory manipulations during research studies.

Results

Normal laboratory procedures used to process the influenza virus were carried out independently and the amount of virus polluting the on-site atmosphere was measured. In particular, zootomy, grinding, centrifugation, pipetting, magnetic stirring, egg inoculation, and experimental zoogenetic infection were performed. In addition,

SUBMITTER: Li Z 

PROVIDER: S-EPMC3439333 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature