Efficacy of Olibra: a 12-week randomized controlled trial and a review of earlier studies.

ABSTRACT:

Background

Intervention strategies that harness the body's appetite and satiety regulating signals provide a means of countering excessive energy intake.

Methods

Eighty-two subjects were enrolled (18-60 years, body mass index: 25-40 kg/m(2)) in a randomized, placebo-controlled, double-blind, parallel trial. During a 12-week period, the effects of Olibra™ fat emulsion (2.1 g twice daily) on food intake, appetite, satiety, weight, and body composition were compared with those of a twice daily administered placebo (1.95 g milk fat). On days -7, 0, and 28, Olibra or the placebo added to 200 g of yogurt was served at breakfast and lunch. Food intake, appetite, and satiety were assessed after lunch and dinner. Body weight was measured on days -7, 0, 14, 28, 56, and 84. Body fat, w

SUBMITTER: Rebello CJ 

PROVIDER: S-EPMC3440037 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature