Viruses in nondisinfected drinking water from municipal wells and community incidence of acute gastrointestinal illness.

ABSTRACT:

Background

Groundwater supplies for drinking water are frequently contaminated with low levels of human enteric virus genomes, yet evidence for waterborne disease transmission is lacking.

Objectives

We related quantitative polymerase chain reaction (qPCR)-measured enteric viruses in the tap water of 14 Wisconsin communities supplied by nondisinfected groundwater to acute gastrointestinal illness (AGI) incidence.

Methods

AGI incidence was estimated from health diaries completed weekly by households within each study community during four 12-week periods. Water samples were collected monthly from five to eight households per community. Viruses were measured by qPCR, and infectivity assessed by cell culture. AGI incidence was related to virus measures using Poisson regre

SUBMITTER: Borchardt MA 

PROVIDER: S-EPMC3440111 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature