Insect Innate Immunity Database (IIID): an annotation tool for identifying immune genes in insect genomes.

ABSTRACT: The innate immune system is an ancient component of host defense. Since innate immunity pathways are well conserved throughout many eukaryotes, immune genes in model animals can be used to putatively identify homologous genes in newly sequenced genomes of non-model organisms. With the initiation of the "i5k" project, which aims to sequence 5,000 insect genomes by 2016, many novel insect genomes will soon become publicly available, yet few annotation resources are currently available for insects. Thus, we developed an online tool called the Insect Innate Immunity Database (IIID) to provide an open access resource for insect immunity and comparative biology research (http://www.vanderbilt.edu/IIID). The database provides users with simple exploratory tools to search the immune repertoires of

SUBMITTER: Brucker RM 

PROVIDER: S-EPMC3440344 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature