Ginkgo biloba does not improve cognitive function in MS: a randomized placebo-controlled trial.

ABSTRACT:

Objective

To determine whether Ginkgo biloba extract (ginkgo) improves cognitive function in persons with multiple sclerosis (MS).

Methods

Persons with MS from the Seattle and Portland VA clinics and adjacent communities who scored 1 SD or more below the mean on one of 4 neuropsychological tests (Stroop Test, California Verbal Learning Test II [CVLT-II], Controlled Oral Word Association Test [COWAT], and Paced Auditory Serial Addition Task [PASAT]) were randomly assigned to receive either one 120-mg tablet of ginkgo (EGb-761; Willmar Schwabe GmbH & Co, Germany) or one placebo tablet twice a day for 12 weeks. As the primary outcome, we compared the performance of the 2 groups on the 4 tests at exit after adjusting for baseline performance.

Results

Fifty-nine subjects r

SUBMITTER: Lovera JF 

PROVIDER: S-EPMC3440446 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature