Development and validation of the Pediatric Epilepsy Side Effects Questionnaire.

ABSTRACT:

Objective

To develop and validate a measure of antiepileptic drug (AED) side effects in children with a variety of seizure types, treatments, and therapy durations.

Methods

Content for an initial 44-item measure was developed using the previously published Hague Scale and expert opinion from recognized pediatric epileptologists (n = 12) and caregivers of children with epilepsy (n = 21). The measure was completed by caregivers during routine clinic visits. Demographic and medical data were collected through chart reviews. Factor analysis was conducted and internal consistency, test-retest reliability, and construct validity were assessed.

Results

Questionnaires were analyzed from 495 children with epilepsy (M(age) = 10.1 years; range 2-21 years; 42% female; 14% African

SUBMITTER: Morita DA 

PROVIDER: S-EPMC3440448 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature