Neurologic outcomes in retinopathy-negative cerebral malaria survivors.

ABSTRACT:

Objectives

Patients surviving retinopathy-positive cerebral malaria (CM) are at high risk for the development of epilepsy, developmental disabilities, and behavioral abnormalities. We aimed to establish whether retinopathy-negative CM is also a risk factor for these outcomes.

Methods

Between 2005 and 2007, survivors of CM and concurrently hospitalized controls in Blantyre, Malawi, were followed to assess the development of neurologic abnormalities. At discharge and every 3 months thereafter, incident cases of epilepsy and developmental disabilities were ascertained using screening questionnaires and confirmatory neurologic examinations. Incident cases of epilepsy and developmental disabilities were compared in retinopathy-negative CM survivors to controls and retinopathy-pos

SUBMITTER: Postels DG 

PROVIDER: S-EPMC3440452 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature