Characterization and differential expression of microRNAs elicited by sulfur deprivation in Chlamydomonas reinhardtii.

ABSTRACT:

Background

microRNAs (miRNAs) have been found to play an essential role in the modulation of numerous biological processes in eukaryotes. Chlamydomonas reinhardtii is an ideal model organism for the study of many metabolic processes including responses to sulfur-deprivation. We used a deep sequencing platform to extensively profile and identify changes in the miRNAs expression that occurred under sulfur-replete and sulfur-deprived conditions. The aim of our research was to characterize the differential expression of Chlamydomonas miRNAs under sulfur-deprived conditions, and subsequently, the target genes of miRNA involved in sulfur-deprivation were further predicted and analyzed.

Results

By using high-throughput sequencing, we characterized the microRNA transcriptomes under

SUBMITTER: Shu L 

PROVIDER: S-EPMC3441669 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature