Target mimics: an embedded layer of microRNA-involved gene regulatory networks in plants.

ABSTRACT:

Background

MicroRNAs (miRNAs) play an essential role in gene regulation in plants. At the same time, the expression of miRNA genes is also tightly controlled. Recently, a novel mechanism called "target mimicry" was discovered, providing another layer for modulating miRNA activities. However, except for the artificial target mimics manipulated for functional studies on certain miRNA genes, only one example, IPS1 (Induced by Phosphate Starvation 1)-miR399 was experimentally confirmed in planta. To date, few analyses for comprehensive identification of natural target mimics have been performed in plants. Thus, limited evidences are available to provide detailed information for interrogating the questionable issue whether target mimicry was widespread in planta, and implicated in certa

SUBMITTER: Meng Y 

PROVIDER: S-EPMC3441763 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature