Prediction of pain sensitivity in healthy volunteers.

ABSTRACT:

Purpose

The primary objective of the present study was to evaluate predictive parameters of the acute pain score during induction of an inflammatory heat injury.

Patients and methods

Healthy volunteers (50 females/50 males) were included in the study. The predictive potential of gender, anthropometric (body surface area, body mass index), psychological (anxiety, depression, vulnerability), and psychophysical (quantitative sensory testing, conditioned pain modulation) variables in estimating the pain response to a validated heat injury (47°C, 7 minutes, area 12.5 cm(2)) were investigated. All assessments were made in duplicate sessions separated by 21 days (median).

Results

There were three main findings in this study. First, a predictive model of pain sensitivity duri

SUBMITTER: Ravn P 

PROVIDER: S-EPMC3442738 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature