Genetic architecture of body size in mammals.

ABSTRACT: Much of the heritability for human stature is caused by mutations of small-to-medium effect. This is because detrimental pleiotropy restricts large-effect mutations to very low frequencies.

SUBMITTER: Kemper KE 

PROVIDER: S-EPMC3446298 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature