The multiplicity of divergence mechanisms in a single evolving population.

ABSTRACT:

Background

Evolutionary divergence is common within bacterial species and populations, even during a single bacterial infection. We use large-scale genomic and phenotypic analysis to identify the extent of diversification in controlled experimental populations and apply these data to differentiate between several potential mechanisms of evolutionary divergence.

Results

We defined testable differences between five proposed mechanisms and used experimental evolution studies to follow eight glucose-limited Escherichia coli chemostat populations at two growth rates. Simple phenotypic tests identified 11 phenotype combinations evolving under glucose limitation. Each evolved population exhibited 3 to 5 different combinations of the 11 phenotypic clusters. Genome sequencing of a re

SUBMITTER: Maharjan RP 

PROVIDER: S-EPMC3446313 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature