MicrobesFlux: a web platform for drafting metabolic models from the KEGG database.

ABSTRACT:

Background

Concurrent with the efforts currently underway in mapping microbial genomes using high-throughput sequencing methods, systems biologists are building metabolic models to characterize and predict cell metabolisms. One of the key steps in building a metabolic model is using multiple databases to collect and assemble essential information about genome-annotations and the architecture of the metabolic network for a specific organism. To speed up metabolic model development for a large number of microorganisms, we need a user-friendly platform to construct metabolic networks and to perform constraint-based flux balance analysis based on genome databases and experimental results.

Results

We have developed a semi-automatic, web-based platform (MicrobesFlux) for generatin

SUBMITTER: Feng X 

PROVIDER: S-EPMC3447728 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature