Association of low serum 25-hydroxyvitamin D levels and mortality in the critically ill.

ABSTRACT:

Objective

We hypothesized that deficiency in 25-hydroxyvitamin D before hospital admission would be associated with all-cause mortality in the critically ill.

Design

Multicenter observational study of patients treated in medical and surgical intensive care units.

Setting

A total of 209 medical and surgical intensive care beds in two teaching hospitals in Boston, MA.

Patients

A total of 2399 patients, age ≥ 18 yrs, in whom 25-hydroxyvitamin D was measured before hospitalization between 1998 and 2009.

Interventions

None.

Measurements and main results

Preadmission 25-hydroxyvitamin D was categorized as deficiency in 25-hydroxyvitamin D (≤ 15 ng/mL), insufficiency (16-29 ng/mL), and sufficiency (≥ 30 ng/mL). Logistic regression examined death by days

SUBMITTER: Braun A 

PROVIDER: S-EPMC3448785 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature