Sleep disturbances and risk of frailty and mortality in older men.

ABSTRACT:

Objective

To test the hypothesis that non-frail older men with poorer sleep at baseline are at increased risk of frailty and death at follow-up.

Methods

In this prospective cohort study, subjective (questionnaires) and objective sleep parameters (actigraphy, in-home overnight polysomnography) were measured at baseline in 2505 non-frail men aged ≥67years. Repeat frailty status assessment performed an average of 3.4 years later; vital status assessed every four months. Sleep parameters expressed as dichotomized predictors using clinical cut-points. Status at follow-up exam classified as robust, intermediate (pre-frail) stage, frail, or died in interim.

Results

None of the sleep disturbances were associated with the odds of being intermediate/frail/dead (vs. robust) at f

SUBMITTER: Ensrud KE 

PROVIDER: S-EPMC3449012 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature