Pd-catalyzed C-H fluorination with nucleophilic fluoride.

ABSTRACT: The palladium-catalyzed C-H fluorination of 8-methylquinoline derivatives with nucleophilic fluoride is reported. This transformation involves the use of AgF as the fluoride source in combination with a hypervalent iodine oxidant. Both the scope and mechanism of the reaction are discussed.

SUBMITTER: McMurtrey KB 

PROVIDER: S-EPMC3449219 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature