In-silico comparative study of inhibitory mechanism of Plant Serine Proteinase Inhibitors.

ABSTRACT: The nematodes like root-knot and cyst are plant-parasitic pest found in horticultural and agricultural crops. They do damages in the roots of plants as a result losses million tons of production. High cost of nematicides and environment safety concern has necessitated finding of some alternative methods. Under Integrated Pest Management (IPM) such problems are solving significantly by means of target gene inhibition, agrobacterium mediated transformation etc. One of this strategy use Plant Proteinase Inhibitors (PIs) gene which are used to control the proteolysis mechanism of Pest by inhibiting gut Serine Proteinase (SP). Present work investigates the utility of computer aided methods to study the mechanism of Protein-Protein interactions and thereby inhibition of Serine Proteinase by PIs.

SUBMITTER: Siva Prasad CV 

PROVIDER: S-EPMC3449373 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature