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Ectoine biosynthesis in Mycobacterium smegmatis.


ABSTRACT: Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M. smegmatis halotolerance and of the molecular mechanism that supports it.

SUBMITTER: Ofer N 

PROVIDER: S-EPMC3457100 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature