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Complete genome sequence of a tenth human polyomavirus.

ABSTRACT: Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based analysis of condyloma specimens from a patient with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome demonstrated the presence of a tenth apparently human-tropic polyomavirus species, which we name HPyV10.

SUBMITTER: Buck CB 

PROVIDER: S-EPMC3457262 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

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Complete genome sequence of a tenth human polyomavirus.

Buck Christopher B CB   Phan Giao Q GQ   Raiji Manish T MT   Murphy Philip M PM   McDermott David H DH   McBride Alison A AA  

Journal of virology 20121001 19

Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based analysis of condyloma specimens from a patient with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome demonstrated the presence of a tenth apparently human-tropic polyomavirus species, which we name HPyV10. ...[more]

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