Ontology highlight
ABSTRACT:
SUBMITTER: Chauvel M
PROVIDER: S-EPMC3457969 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Chauvel Murielle M Nesseir Audrey A Cabral Vitor V Znaidi Sadri S Goyard Sophie S Bachellier-Bassi Sophie S Firon Arnaud A Legrand Mélanie M Diogo Dorothée D Naulleau Claire C Rossignol Tristan T d'Enfert Christophe C
PloS one 20120925 9
Candida albicans is the most frequently encountered human fungal pathogen, causing both superficial infections and life-threatening systemic diseases. Functional genomic studies performed in this organism have mainly used knock-out mutants and extensive collections of overexpression mutants are still lacking. Here, we report the development of a first generation C. albicans ORFeome, the improvement of overexpression systems and the construction of two new libraries of C. albicans strains overexp ...[more]