Detailed transcriptome description of the neglected cestode Taenia multiceps.

ABSTRACT:

Background

The larval stage of Taenia multiceps, a global cestode, encysts in the central nervous system (CNS) of sheep and other livestock. This frequently leads to their death and huge socioeconomic losses, especially in developing countries. This parasite can also cause zoonotic infections in humans, but has been largely neglected due to a lack of diagnostic techniques and studies. Recent developments in next-generation sequencing provide an opportunity to explore the transcriptome of T. multiceps.

Methodology/principal findings

We obtained a total of 31,282 unigenes (mean length 920 bp) using Illumina paired-end sequencing technology and a new Trinity de novo assembler without a referenced genome. Individual transcription molecules were determined by sequence-based annot

SUBMITTER: Wu X 

PROVIDER: S-EPMC3458062 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature