Cation affinity numbers of Lewis bases.

ABSTRACT: Using selected theoretical methods the affinity of a large range of Lewis bases towards model cations has been quantified. The range of model cations includes the methyl cation as the smallest carbon-centered electrophile, the benzhydryl and trityl cations as models for electrophilic substrates encountered in Lewis base-catalyzed synthetic procedures, and the acetyl cation as a substrate model for acyl-transfer reactions. Affinities towards these cationic electrophiles are complemented by data for Lewis-base addition to Michael acceptors as prototypical neutral electrophiles.

SUBMITTER: Lindner C 

PROVIDER: S-EPMC3458768 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature