Can diversifying selection be distinguished from history in geographic clines? A population genomic study of killifish (Fundulus heteroclitus).

ABSTRACT: A common geographical pattern of genetic variation is the one-dimensional cline. Clines may be maintained by diversifying selection across a geographical gradient but can also reflect historical processes such as allopatry followed by secondary contact. To identify loci that may be undergoing diversifying selection, we examined the distribution of geographical variation patterns across the range of the killifish (Fundulus heteroclitus) in 310 loci, including microsatellites, allozymes, and single nucleotide polymorphisms. We employed two approaches to detect loci under strong diversifying selection. First, we developed an automated method to identify clinal variation on a per-locus basis and examined the distribution of clines to detect those that exhibited signifcantly steeper slopes. Sec

SUBMITTER: Strand AE 

PROVIDER: S-EPMC3458873 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature