Rich club organization of macaque cerebral cortex and its role in network communication.

ABSTRACT: Graph-theoretical analysis of brain connectivity data has revealed significant features of brain network organization across a range of species. Consistently, large-scale anatomical networks exhibit highly nonrandom attributes including an efficient small world modular architecture, with distinct network communities that are interlinked by hub regions. The functional importance of hubs motivates a closer examination of their mutual interconnections, specifically to examine the hypothesis that hub regions are more densely linked than expected based on their degree alone, i.e. forming a central rich club. Extending recent findings of rich club topology in the cat and human brain, this report presents evidence for the existence of rich club organization in the cerebral cortex of a non-human p

SUBMITTER: Harriger L 

PROVIDER: S-EPMC3460908 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature