NIDCAP improves brain function and structure in preterm infants with severe intrauterine growth restriction.

ABSTRACT:

Objective

The effect of NIDCAP (Newborn Individualized Developmental Care and Assessment Program) was examined on the neurobehavioral, electrophysiological and neurostructural development of preterm infants with severe intrauterine growth restriction (IUGR).

Study design

A total of 30 infants, 27-33 weeks gestation, were randomized to control (C; N=17) or NIDCAP/experimental (E; N=13) care. Baseline health and demographics were assessed at intake; electroencephalography (EEG) and magnetic resonance imaging (MRI) at 35 and 42 weeks postmenstrual age; and health, growth and neurobehavior at 42 weeks and 9 months corrected age (9 months).

Results

C and E infants were comparable in health and demographics at baseline. At follow-up, E infants were healthier, showed signifi

SUBMITTER: Als H 

PROVIDER: S-EPMC3461405 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature