Ontology highlight
ABSTRACT:
SUBMITTER: Huang W
PROVIDER: S-EPMC3465439 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Huang Wen W Richards Stephen S Carbone Mary Anna MA Zhu Dianhui D Anholt Robert R H RR Ayroles Julien F JF Duncan Laura L Jordan Katherine W KW Lawrence Faye F Magwire Michael M MM Warner Crystal B CB Blankenburg Kerstin K Han Yi Y Javaid Mehwish M Jayaseelan Joy J Jhangiani Shalini N SN Muzny Donna D Ongeri Fiona F Perales Lora L Wu Yuan-Qing YQ Zhang Yiqing Y Zou Xiaoyan X Stone Eric A EA Gibbs Richard A RA Mackay Trudy F C TF
Proceedings of the National Academy of Sciences of the United States of America 20120904 39
Epistasis-nonlinear genetic interactions between polymorphic loci-is the genetic basis of canalization and speciation, and epistatic interactions can be used to infer genetic networks affecting quantitative traits. However, the role that epistasis plays in the genetic architecture of quantitative traits is controversial. Here, we compared the genetic architecture of three Drosophila life history traits in the sequenced inbred lines of the Drosophila melanogaster Genetic Reference Panel (DGRP) an ...[more]