Increasing the efficacy of bioorthogonal click reactions for bioconjugation: a comparative study.

ABSTRACT: Raising the bar: the efficacy of bioorthogonal reactions for bioconjugation has been thoroughly evaluated in four different biological settings. Powered by the development of new biocompatible ligands, the copper-catalyzed azide-alkyne cycloaddition has brought about unsurpassed bioconjugation efficiency, and thus it holds great promise as a highly potent and adaptive tool for a broader spectrum of biological applications.

SUBMITTER: Besanceney-Webler C 

PROVIDER: S-EPMC3465470 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature