Ontology highlight
ABSTRACT:
SUBMITTER: Zhao X
PROVIDER: S-EPMC3465925 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
ISRN endocrinology 20120929
GLP-1 and its analog have been used in diabetes treatment; however, the direct alteration of gene expression profile in human islets induced by GLP-1 has not been reported. In present study, transcriptional gene expression in the liraglutide-treated human islets was analyzed with 12 human U133A chips including 23000 probe sets. The data compared between liraglutide and control groups showed a significant difference on glucose-induced insulin secretion, rather than viability. Microarray analysis ...[more]