Comparing thousands of circular genomes using the CGView Comparison Tool.

ABSTRACT:

Background

Continued sequencing efforts coupled with advances in sequencing technology will lead to the completion of a vast number of small genomes. Whole-genome comparisons represent an important part of the analysis of any new genome sequence, as they can provide a better understanding of the biology and evolution of the source organism. Visualization of the results is important, as it allows information from a variety of sources to be integrated and interpreted. However, existing graphical comparison tools lack features needed for efficiently comparing a new genome to hundreds or thousands of existing sequences. Moreover, existing tools are limited in terms of the types of comparisons that can be performed, the extent to which the output can be customized, and the ease with whi

SUBMITTER: Grant JR 

PROVIDER: S-EPMC3469350 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature