The many landscapes of recombination in Drosophila melanogaster.

ABSTRACT: Recombination is a fundamental biological process with profound evolutionary implications. Theory predicts that recombination increases the effectiveness of selection in natural populations. Yet, direct tests of this prediction have been restricted to qualitative trends due to the lack of detailed characterization of recombination rate variation across genomes and within species. The use of imprecise recombination rates can also skew population genetic analyses designed to assess the presence and mode of selection across genomes. Here we report the first integrated high-resolution description of genomic and population variation in recombination, which also distinguishes between the two outcomes of meiotic recombination: crossing over (CO) and gene conversion (GC). We characterized the prod

SUBMITTER: Comeron JM 

PROVIDER: S-EPMC3469467 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature