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GOx signaling triggered by aptamer-based ATP detection.

ABSTRACT: Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response.

SUBMITTER: Sitaula S 

PROVIDER: S-EPMC3470447 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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GOx signaling triggered by aptamer-based ATP detection.

Sitaula Sarita S   Branch Shirmir D SD   Ali Mehnaaz F MF  

Chemical communications (Cambridge, England) 20120809 74

Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response. ...[more]

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