Dental composite restorations and neuropsychological development in children: treatment level analysis from a randomized clinical trial.

ABSTRACT:

Background

Resin-based dental restorations may intra-orally release their components and bisphenol A. Gestational bisphenol A exposure has been associated with poorer executive functioning in children.

Objectives

To examine whether exposure to resin-based composite restorations is associated with neuropsychological development in children.

Methods

Secondary analysis of treatment level data from the New England Children's Amalgam Trial, a 2-group randomized safety trial conducted from 1997 to 2006. Children (N=534) aged 6-10 y with ≥2 posterior tooth caries were randomized to treatment with amalgam or resin-based composites (bisphenol-A-diglycidyl-dimethacrylate-composite for permanent teeth; urethane dimethacrylate-based polyacid-modified compomer for primary teeth).

SUBMITTER: Maserejian NN 

PROVIDER: S-EPMC3470777 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature