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Spread of influenza virus A (H5N1) clade 2.3.2.1 to Bulgaria in common buzzards.

ABSTRACT: On March 15, 2010, a highly pathogenic avian influenza virus was isolated from the carcass of a common buzzard (Buteo buteo) in Bulgaria. Phylogenetic analyses of the virus showed a close genetic relationship with influenza virus A (H5N1) clade 2.3.2.1 viruses isolated from wild birds in the Tyva Republic and Mongolia during 2009-2010. Designated A/common buzzard/Bulgaria/38WB/2010, this strain was highly pathogenic in chickens but had low pathogenicity in mice and ferrets and no molecular markers of increased pathogenicity in mammals. The establishment of clade 2.3.2.1 highly pathogenic avian influenza viruses of the H5N1 subtype in wild birds in Europe would increase the likelihood of health threats to humans and poultry in the region.

SUBMITTER: Marinova-Petkova A

PROVIDER: S-EPMC3471626 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

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Spread of influenza virus A (H5N1) clade 2.3.2.1 to Bulgaria in common buzzards.

Marinova-Petkova Atanaska A Georgiev Georgi G Seiler Patrick P Darnell Daniel D Franks John J Krauss Scott S Webby Richard J RJ Webster Robert G RG

Emerging infectious diseases 20121001 10

On March 15, 2010, a highly pathogenic avian influenza virus was isolated from the carcass of a common buzzard (Buteo buteo) in Bulgaria. Phylogenetic analyses of the virus showed a close genetic relationship with influenza virus A (H5N1) clade 2.3.2.1 viruses isolated from wild birds in the Tyva Republic and Mongolia during 2009-2010. Designated A/common buzzard/Bulgaria/38WB/2010, this strain was highly pathogenic in chickens but had low pathogenicity in mice and ferrets and no molecular marke ...[more]

PMID: 23017273

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