CMD: A Database to Store the Bonding States of Cysteine Motifs with Secondary Structures.

ABSTRACT: Computational approaches to the disulphide bonding state and its connectivity pattern prediction are based on various descriptors. One descriptor is the amino acid sequence motifs flanking the cysteine residue motifs. Despite the existence of disulphide bonding information in many databases and applications, there is no complete reference and motif query available at the moment. Cysteine motif database (CMD) is the first online resource that stores all cysteine residues, their flanking motifs with their secondary structure, and propensity values assignment derived from the laboratory data. We extracted more than 3 million cysteine motifs from PDB and UniProt data, annotated with secondary structure assignment, propensity value assignment, and frequency of occurrence and coefficiency of the

SUBMITTER: Bostan H 

PROVIDER: S-EPMC3474208 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature