Reversion from mild cognitive impairment to normal or near-normal cognition: risk factors and prognosis.

ABSTRACT:

Objectives

We sought to identify characteristics of individuals with mild cognitive impairment (MCI) that are associated with a relatively high probability of reverting back to normal cognition, and to estimate the risk of future cognitive decline among those who revert.

Methods

We first studied 3,020 individuals diagnosed with MCI on at least 1 visit to an Alzheimer's Disease Center in the United States. All underwent standardized Uniform Data Set evaluations at their first visit with an MCI diagnosis and on a subsequent visit, about 1 year later, at which cognitive status was reassessed. Multiple logistic regression was used to identify predictors of reverting from MCI back to normal cognition. We then estimated the risk of developing MCI or dementia over the next 3 years

SUBMITTER: Koepsell TD 

PROVIDER: S-EPMC3475624 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature