Epidemiological, molecular and clinical features of enterovirus 109 infection in children and in adult stem cell transplant recipients.

ABSTRACT:

Background

A novel human enterovirus (HEV) type within the species HEV-C, named EV109, was discovered from cases of respiratory illness in Nicaragua in September 2010. The aim of this study, was to retrospectively examine the presence and the role of EV109 in respiratory samples from two patients populations; infants below the age of 2 years, hospitalized for acute respiratory diseases (ARDs) and adult hematopoietic stem cell transplantation recipients.

Results

A total of 1149 nasopharingeal aspirates were collected and tested for the presence of EV109 by reverse transcription-PCR (RT-PCR). In positive samples, the presence of the most common respiratory viruses was also assayed and clinical symptoms were evaluated. Samples from 2 of the 974 infants tested positive for EV109

SUBMITTER: Debiaggi M 

PROVIDER: S-EPMC3477084 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature